Released on: March 5, 2008, 2:53 am

Press Release Author: Thermo Fisher Scientific

Industry:

Press Release Summary: Thermo Fisher Scientific Inc., the world leader in serving
science, today announced that its award-winning Thermo Scientific LTQ Orbitrap®
hybrid series of mass spectrometers are now available with electron transfer
dissociation (ETD) and matrix-assisted laser desorption/ionization (MALDI)
capabilities. The LTQ Orbitrap XL ETD is the only ETD instrument with both high
resolution and accurate mass, enabling definitive protein characterization during
mass spectrometry (MS). The new MALDI LTQ Orbitrap series simplifies the analysis of
whole tissue, biological and polymer samples by eliminating sample preparation. The
new LTQ Orbitrap capabilities will be showcased at the Thermo Scientific booth 1741
at PITTCON 2008, being held March 3 - 6 in New Orleans.

Press Release Body: FOR IMMEDIATE RELEASE
Mass Spectrometry
Media Contact Information:
Name: Laura Browne/Charlotte Culley
Phone: +44 1477 539539
Email: thermo@scottpr.com
Website: www.scottpr.com

Secondary Contact Information:
Stephanie Kubina
+1 408-965-6022
stephanie.kubina@thermofisher.com
www.thermo.com/orbitrap

Thermo Fisher Scientific Extends LTQ Orbitrap Mass Spectrometry Performance in
Proteomics with ETD and MALDI Capabilities

NEW ORLEANS (March 5, 2008) - Thermo Fisher Scientific Inc., the world leader in
serving science, today announced that its award-winning Thermo Scientific LTQ
Orbitrap® hybrid series of mass spectrometers are now available with electron
transfer dissociation (ETD) and matrix-assisted laser desorption/ionization (MALDI)
capabilities. The LTQ Orbitrap XL ETD is the only ETD instrument with both high
resolution and accurate mass, enabling definitive protein characterization during
mass spectrometry (MS). The new MALDI LTQ Orbitrap series simplifies the analysis of
whole tissue, biological and polymer samples by eliminating sample preparation. The
new LTQ Orbitrap capabilities will be showcased at the Thermo Scientific booth 1741
at PITTCON 2008, being held March 3 - 6 in New Orleans.

Thermo Scientific ETD technology enables highly sensitive post-translational
modification analyses. Combined with the power of the LTQ Orbitrap XL, ETD completes
the most advanced proteomics platform available by offering three complementary
fragmentation techniques in one instrument. It can be used for definitive
protein/peptide characterization, post-translational modification (PTM) analysis
(especially phosphorylation) and top-down or middle-down sequencing of proteins and
peptides.

"Introduction of ETD on an LTQ Orbitrap is a landmark event in the field of
proteomics," said renowned proteomics researcher Steven P. Gygi, PhD. "ETD is what
is next for mainstream and cutting-edge proteomics applications. Its usefulness is
so broad that I can\'t imagine a research or core mass spectrometry lab without this
new system in the future."

The new MALDI source, available on the LTQ Orbitrap XL and Discovery, is ideally
suited for proteomic and metabolism applications. For the first time, resolutions of
greater than 50,000 FWHM and mass accuracies of 1-2 ppm are routinely available for
MS, MS/MS and even MSn data. Using the high-resolving power and outstanding mass
accuracy of the LTQ Orbitrap, researchers can now perform peptide and protein
identification of MALDI-produced ions. Other important applications include the
high-throughput analysis of in-gel digests of 2D gel spots, de novo sequencing,
iTRAQT quantitation*, tissue imaging and small molecule analysis.

"The addition of these two key capabilities to the premier Thermo Scientific
Orbitrap technology platform is a significant advancement for the world of
proteomics and metabolomics," said Dr. Ian Jardine, vice president of global
research and development for Thermo Fisher Scientific. "Thermo Fisher is dedicated
to developing innovations for its customers that embrace the most sophisticated
analytical technologies available for their applications. This is clearly
demonstrated with the introduction of the most comprehensive proteomics platform
available on the market."

For more information on the new capabilities available on the Thermo Scientific LTQ
Orbitrap hybrid mass spectrometer, please visit booth 1741 at PITTCON 2008.
Alternatively, please email analyze@thermofisher.com, call +1 800-532-4752 or visit
www.thermo.com/orbitrap.

* iTRAQ is a trademark of Applera Corporation.

Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving
science.

About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science,
enabling our customers to make the world healthier, cleaner and safer. With annual
revenues of $10 billion, we have more than 30,000 employees and serve over 350,000
customers within pharmaceutical and biotech companies, hospitals and clinical
diagnostic labs, universities, research institutions and government agencies, as
well as environmental and industrial process control settings. Serving customers
through two premier brands, Thermo Scientific and Fisher Scientific, we help solve
analytical challenges from routine testing to complex research and discovery. Thermo
Scientific offers customers a complete range of high-end analytical instruments as
well as laboratory equipment, software, services, consumables and reagents to enable
integrated laboratory workflow solutions. Fisher Scientific provides a complete
portfolio of laboratory equipment, chemicals, supplies and services used in
healthcare, scientific research, safety and education. Together, we offer the most
convenient purchasing options to customers and continuously advance our technologies
to accelerate the pace of scientific discovery, enhance value for customers and fuel
growth for shareholders and employees alike. Visit www.thermofisher.com.

For further press information please contact: Laura Browne, The Scott Partnership, 1
Whiteside, Station Road, Holmes Chapel, Cheshire. CW4 8AA United Kingdom Tel: +44
1477 539539 Fax: +44 1606 1477 539540 Email: thermo@scottpr.com

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Contact Details: THE SCOTT PARTNERSHIP
1 WHITESIDE
STATION ROAD
HOLMES CHAPEL
CHESHIRE
CW4 8AA
UK
01477 539539
thermo@scottpr.com